Sometime this year I revisited an episode of Boston Legal where a teenager keeps on playing video game for some 36 hours without leaving his seat even for a minute and the dopamine levels in his brain increased to such high levels causing brain freeze and instant death. Addicts out there beware to take rests at regular levels.
P.S.: Dopamine is a pleasure receptor in the brain. Like when you take drugs and get high it increases the level of dopamine released to the brain to give a higher level of pleasure.